英语翻译In accordance with previous data reported in the literature ,this study confirms the occurrence of lymphocytopenia(淋巴细胞减少) inmetastatic neoplastic disease(发生转移的肿瘤).The problem,however,of cancerrelatedlymphocy
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英语翻译In accordance with previous data reported in the literature ,this study confirms the occurrence of lymphocytopenia(淋巴细胞减少) inmetastatic neoplastic disease(发生转移的肿瘤).The problem,however,of cancerrelatedlymphocy
英语翻译
In accordance with previous data reported in the literature ,
this study confirms the occurrence of lymphocytopenia(淋巴细胞减少) in
metastatic neoplastic disease(发生转移的肿瘤).The problem,however,of cancerrelated
lymphocytopenia is to establish if it is characterized by
a general decline in the overall lymphocyte subsets(淋巴细胞亚群) or if it may
depend on a deficiency of a particular cell subset.The results
of this study,by showing an increase in the proportion of T-reg
lymphocytes in metastatic patients,identified as CD4+CD25+
cells,would suggest that the decline in lymphocyte number
related to cancer progression is due to a selective deficiency of
immune cells responsible for the generation of an effective
antitumor immunoreaction(抗肿瘤免疫),such as T-helper lymphocytes.
Moreover,with respect to the results of others showing an
association between cancer progression and increase in T-reg(调节性T细胞)
generation,the study demonstrates that an increase in
the absolute number of T-reg lymphocytes may only be
observed in metastatic patients,with normal lymphocyte count,
whereas lymphocytopenic cancer patients may present a normal
or a paradoxically low number of T-reg cells.In contrast,by
considering the percentage of T-reg cells in relation to that of
total lymphocyte and T-helper cells,the study confirm that
metastatic disease is constantly associated with an abnormally
increased generation of T-reg cells,which are responsible for
the suppression of an effective anticancer immune reaction.
Therefore,the evaluation of T-reg lymphocyte numbers in terms
of their percentage with respect to the total number of CD4+
lymphocytes(CD4+淋巴细胞) would be a more appropriate clinical
immunological parameter than the measurement of their
absolute numbers.The CD4+/CD4+CD25+ ratio could
constitute a new simple clinical immunological index capable
of assessing the anticancer immune function in cancer patients.
英语翻译In accordance with previous data reported in the literature ,this study confirms the occurrence of lymphocytopenia(淋巴细胞减少) inmetastatic neoplastic disease(发生转移的肿瘤).The problem,however,of cancerrelatedlymphocy
依照先前的,在文献中的(试验)数据报告.这个研究证实了,在发生肿瘤转移的疾病中,淋巴细胞减少(症)的出现.然而,问题是:癌症相关的淋巴细胞减少(症)确立于,是在整体的淋巴细胞亚群中一种总体的下降,还是取决于一种特定的单一细胞群的缺乏.这个研究的结果是,在发生肿瘤转移的病人身上,显示出一定比例的抑制性T[淋巴]细胞(或者调节性T细胞)的增长,这种细胞被识别出为(CD4+CD25+细胞).由于一种选定的免疫细胞,负责有效的(抗肿瘤免疫)的生成.例如:T辅助(淋巴)细胞,暗示了淋巴细胞数量相关的癌症级数.
更多的,基于其他的结果显示出,一种癌症级数和抑制性T[淋巴]细胞(或者调节性T细胞).这个研究论证了绝对数量的调节性T细胞也许只能在发生肿瘤转移的病人身上(正常的淋巴细胞数量,和淋巴细胞减少的癌症病患者)观察到,因为他们身上所呈现出的正常的或者出乎意料低数量的调节性T细胞.
相反地,由于考虑到调节性T细胞的百分比,与之相关的总体淋巴细胞和T辅助(淋巴)细胞,这个研究证实了:(肿瘤)转移性疾病,经常与反常的增长的调节性T细胞(那些有效的抗癌-免疫反应)相结合.
因此,就(关于CD4+淋巴细胞的总数的百分比)而言,与计算他们的绝对数量,抑制性T[淋巴]细胞(或者调节性T细胞)数量的评估,是可以成为一种很合适的临床的免疫学的参考.在癌症患者身上,这个CD4+/CD4+CD25+比率可以建立一个新的简单的临床的免疫学索引,有力的,针对那些评估抗癌的免疫功能.
.已搞定,纯人工的!绝对保证没有漏掉半个字节!就专业程度来说,这篇文章非本人专业的,所以有些句子结构组织得不是很好!但是每个细节部分,都表现出来了!希望有所帮助(ps:本人留英4年的在校生,忙自己的硕士毕业论文,无聊上来看看,所有没有花很多时间来整理你这篇,见谅!)