how do you do?和nice to meet you.在用法上有什么区别?什么情况下用?还有,it和that作代词有什么区别?怎么用?that不能作主语吗？is that so？

请问How do you do与Nice to meet you的用法和区别? how do you do?A how do you do B nice to meet you C I am fine ,thanks 英语中 How do you do与Nice to meet you的用法和区别是什么?请具体说明 How do you do? How Do You Do? how do you do? how do you do How do you do how do you do How do you do How do you do!和How are you?的区别 how do you do 和how are you 的区别 英语中两个人初次见面认识后是用Nice to meet you!还是How do you do? 第一次见面用nice to meet you ,还是 how do you do? 问候熟人时,应说___________.A.How do you do B.How are you C.Nice to meet you . 请问初次见面时用How do you do还是nice to meet you还是How are you谢了 —Hello,John!A.How are you?B.How do you do?C.Nice to meet you!D.Hi,Ben! How are you ,How do you do ,Nice to meet you,它们之间有什么区别没?