英语翻译萘环的取代点多,单个取代基的相对影响小;苯环的讨论相对简单.而如果两边都做系列的话,双因素的构效会比较混乱.而控制一边不变,另一边讨论构效的话,从化学的可能性和讨论的
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英语翻译萘环的取代点多,单个取代基的相对影响小;苯环的讨论相对简单.而如果两边都做系列的话,双因素的构效会比较混乱.而控制一边不变,另一边讨论构效的话,从化学的可能性和讨论的
英语翻译
萘环的取代点多,单个取代基的相对影响小;苯环的讨论相对简单.而如果两边都做系列的话,双因素的构效会比较混乱.而控制一边不变,另一边讨论构效的话,从化学的可能性和讨论的显著性,肯定是先拿苯环做系列.如果活性不好或者可以更好,就继续讨论萘环那一边.药效团修饰完美后我们会继续研究药代动力学.
英语翻译萘环的取代点多,单个取代基的相对影响小;苯环的讨论相对简单.而如果两边都做系列的话,双因素的构效会比较混乱.而控制一边不变,另一边讨论构效的话,从化学的可能性和讨论的
There are many substituted points in the naphthalene ring,a single substitute may affect a little.The disscussion on naphthalene ring is relatively simple.However,if we take both sides as series,the dual factors construction would be in a confusion.With the control of one side steady to disscuss the other side ,as considering the possibility of chemical and the significance of disscussion,we choose naphthalene ring for series.If it shows a negtive activity or better,then shall we disscuss the other side of the naphthalene ring.After a perfect decoration of the pharmacophore,we can continue our study on pharmacokinetics.
Naphthalene ring instead of point, the relative influence of individual substituent small; Benzene is relatively simple. And if both sides do series, double factors of structure-activity will be chaos...
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Naphthalene ring instead of point, the relative influence of individual substituent small; Benzene is relatively simple. And if both sides do series, double factors of structure-activity will be chaos. But on the control side is constant, the other side of the discussion of structure-activity, from chemical and discuss the possibility of significant, must be to make a series of benzene ring. If the activity is bad or can better, continue to discuss the naphthalene ring side. Pharmacophore modification we will continue to study the pharmacokinetics after perfect
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There are many points can substitute Naphthalene nucleus, so simple substitutent group has less effections to others; the theory of Naphthalene nucleus can be relatively simple. If the two sides of Na...
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There are many points can substitute Naphthalene nucleus, so simple substitutent group has less effections to others; the theory of Naphthalene nucleus can be relatively simple. If the two sides of Naphthalene nucleus(这个地方应该写上上文中“两边”所代表的东西,因为对医学不了解,所以暂时先写的苯环,到时候请根据上下文修改)are having series of theories, the structure activity of two-factor will be disordered. But from the possibility of Chemistry and the significance of discussion, if one side is under control and having no changes, and the other side is still discussed to be structed, Naphthalene nucleus will become a series first. No matter the activity is good or not, the discussion of Naphthalene nucleus will be proceeded continuously. When we finish the modification of pharmacophore perfectly, we will continue the research of pharmacokinetics.
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