E-box是什么?(基因里的..)
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E-box是什么?(基因里的..)
E-box是什么?(基因里的..)
E-box是什么?(基因里的..)
是一种DNA序列,通常位于在一个启动子区域的基因的上游. It is a transcription factor binding site where the specific sequence of DNA, CANNTG, is recognized by proteins that can bind to it to help initiate transcription of the gene.它是一种转录因子结合位点,可以绑定到它来帮助启动基因的转录的蛋白质的特定序列的DNA,CANNTG,确认.Once transcription factors bind to promoters, they allow for association of other enzymes which will copy the DNA into mRNA .一旦转录因子结合的启动子,它们允许将复制的DNA到mRNA的其他酶的关联.The consensus sequence for the E-box element is CANNTG, with a palindromic canonical sequence of CACGTG. [ 1 ]Transcription factors containing the basic helix-loop-helix protein structural motif typically bind to E-boxes or related variant sequences and enhance transcription of the downstream gene.共识的E-box元素的顺序 CANNTG,典型的回文序列CACGTG [1]含有基本的螺旋-环-螺旋蛋白的结构基序的转录因子通常绑定到E-盒或相关变体序列和增强转录的下游基因.