The effects of vasodilation on cardiac output measured by PiCCO.【　文献类型　】 期刊论文【　正 题 名　】 The effects of vasodilation on cardiac output measured by PiCCO.【　作　　者　】 Yamashita,K　 Nishiyama,T　 Yokoya

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TheeffectsofvasodilationoncardiacoutputmeasuredbyPiCCO.【　文献类型　】期刊论文【　正题名　】Theeffectsofvasodilationon

The effects of vasodilation on cardiac output measured by PiCCO.【　文献类型　】 期刊论文【　正 题 名　】 The effects of vasodilation on cardiac output measured by PiCCO.【　作　　者　】 Yamashita,K　 Nishiyama,T　 Yokoya
The effects of vasodilation on cardiac output measured by PiCCO.
【　文献类型　】 期刊论文
【　正 题 名　】 The effects of vasodilation on cardiac output measured by PiCCO.
【　作　　者　】 Yamashita,K　 Nishiyama,T　 Yokoyama,T　 Abe,H　 Manabe,M　
【　作者单位　】 Department of Anesthesiology and Critical Care Medicine,Kochi Medical School,Nankoku,Kochi,[email protected]
【　刊　　名　】 Journal of cardiothoracic and vascular anesthesia
【　出版年份　】 2008
【　卷　　期　】 vol.22 no.5
【　　ISSN　　】 1053-0770
【　页　　码　】 P.688-692
【　总 页 数　】 5
【　分 类 号　】 R6　
【　关 键 词　】 Alprostadil　 ug　 Minute of time　 Infusion,NOS　 Vasodilation　 前列地尔　 血管舒张　
【　正文语种　】 eng
【　文　　摘　】 OBJECTIVES:The purpose of this study was to investigate the effects of vasodilation on cardiac output (CO) measured by pulse contour method using PiCCO (Pulsion Medical Systems AG,Munich,Germany) in comparison with CO by the thermodilution method.DESIGN:A prospective observational study.SETTINGS:An operating room in a university hospital.PARTICIPANTS:Twenty patients scheduled for off-pump coronary artery bypass grafting.INTERVENTIONS:After anesthesia induction with midazolam,fentanyl,and vecuronium,the PiCCO catheter and pulmonary artery catheter were inserted.Before the initiation of surgery,progressively higher infusions of prostaglandin E1 (PGE1) were administered for vasodilation.MEASUREMENTS AND MAIN RESULTS:CO was measured before PGE1 (control); at PGE1 0.01,0.02,and 0.04 microg/kg/min; and 15 minutes after stopping PGE1 infusion.Systemic vascular resistances (SVRs) at PGE1 0.02 and 0.04 microg/kg/min were significantly lower than the control value.The correlation coefficient (R(2)) at each point,percentage error,and limits of agreement (bias +/- 2 standard deviation of bias) were 0.89,17,-0.21 +/- 0.53 before PGE1; 0.72,27,-0.31 +/- 0.93 at 0.01 microg/kg/min; 0.53,40,-0.62 +/- 1.41 at 0.02 microg/kg/min; 0.57,34,-0.61 +/- 1.26 at 0.04 microg/kg/min; and 0.97,21,-0.14 +/- 0.69 L/min 15 minutes after the end of infusion,respectively.CONCLUSIONS:PiCCO may not be an alternative to thermodilution measurement without recalibration when SVR decreases by infusion of PGE1 > or = 0.02 microg/kg/min.
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The effects of vasodilation on cardiac output measured by PiCCO.【　文献类型　】 期刊论文【　正 题 名　】 The effects of vasodilation on cardiac output measured by PiCCO.【　作　　者　】 Yamashita,K　 Nishiyama,T　 Yokoya
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