英语翻译Apoptosis has now been widely accepted as a prominent tumour-suppression mechanism.Mutations in certain oncogenes that result in the activation of cell proliferation,such as deregulated MYC expression,require a second mutation to inhibit
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英语翻译Apoptosis has now been widely accepted as a prominent tumour-suppression mechanism.Mutations in certain oncogenes that result in the activation of cell proliferation,such as deregulated MYC expression,require a second mutation to inhibit
英语翻译
Apoptosis has now been
widely accepted as a prominent tumour-suppression
mechanism.Mutations in certain oncogenes that result
in the activation of cell proliferation,such as deregulated
MYC expression,require a second mutation to inhibit
the apoptosis machinery so that tumour promotion can
proceed efficiently.
Thus,the combined overexpression
of BCL-2 and MYC synergize potently in the development of lymphomas and certain other types of cancer7
.myc和bcl2啥关系
英语翻译Apoptosis has now been widely accepted as a prominent tumour-suppression mechanism.Mutations in certain oncogenes that result in the activation of cell proliferation,such as deregulated MYC expression,require a second mutation to inhibit
首先说明本人不是专业的,翻译只为了帮助别人、娱乐自己!内容包含了个人的揣测,仅供参考!
目前,细胞老化作为抑制肿瘤的一个有效的手段已经被普遍接受.某些致癌基因的突变会导致细胞繁殖的活跃,比如 MYC肿瘤基因家族的抑制被解除（活化）,需要再次的基因突变以停止细胞老化,这样肿瘤会开始活跃.
因此,BCL-2和MYC的组合治疗在淋巴癌及一些其他类型癌症方面有显著疗效.
BCL-2和MYC是两种致癌基因,都会诱发癌症,并且都能防止癌细胞老化,他们是并列的关系,这篇文章的意思是这两个方面都要治疗才能有效治愈癌症,大概也就是所谓的靶向治疗吧.