英语翻译LDA was applied to evaluate which of these three ratios provided the maximum discrimination (i.e.,best predictor) between the cell lines.(1,3,28,29) We applied LDA in a stepwise fashion.First,we applied LDA to each polymer separately,wher

英语翻译LDA was applied to evaluate which of these three ratios provided the maximum discrimination (i.e.,best predictor) between the cell lines.(1,3,28,29) We applied LDA in a stepwise fashion.First,we applied LDA to each polymer separately,wher
英语翻译
LDA was applied to evaluate which of these three ratios provided the maximum discrimination (i.e.,best predictor) between the cell lines.(1,3,28,29) We applied LDA in a stepwise fashion.First,we applied LDA to each polymer separately,where we evaluated each potential peak value based on its ability to discriminate between (or predict) the four cell lines.Each of these analyses was conducted using 32 observations (4 cell lines × 8 replications) and 4 variables (the cell line indicator and the three emission intensity wavelength variables).This LDA analyses step identifies the optimal intensity of 410 nm for the P2 polymer and 420 nm for the P1 polymer.
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Other proteins in the conditioned media are interacting with the polymers,causing the observed intensity changes in the emission spectra.While we do not have an explanation yet for the observed pattern of emission intensity changes,we reasoned that these differential modulations can be used to distinguish the cancer cells.In this endeavor,we calculated the ratios of emission intensity (410,510,and 541 nm for P1; 420,520,and 541 nm for P2) in the presence of conditioned and unconditioned culture media (Table S-2,Supporting Information).These ratios were subsequently subjected to linear discriminant analysis (LDA).

英语翻译LDA was applied to evaluate which of these three ratios provided the maximum discrimination (i.e.,best predictor) between the cell lines.(1,3,28,29) We applied LDA in a stepwise fashion.First,we applied LDA to each polymer separately,wher
采用“线性判别分析” 法通过评估四个 细胞系(1,3,28,29)的三个比例中最高的分辨率（既是最佳预测）.我们采取循序渐进的方式进行线性判别分析.首先,我们个别分析每个聚合物,根据其分辨（或预测）四个细胞系的能力来评估每个聚合物的潜在高峰值.每个分析都是采用32个观察 (4细胞系x 8个复制）与4个变量（细胞系指标和3个发射强度的波长变量）.这“线性判别分析” 步骤确认P2聚合物的最优强度是 410 nm ,而P1聚合物则是420 nm .

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