英语翻译在静电作用模式下,克林沙星与DNA骨架上的磷酸基团发生作用,其对ssDNA和dsDNA的猝灭程度应相等,而在插入作用模式下,ssDNA没有dsDNA的双螺旋结构,克林沙星应不对其发生猝灭作用.当发

英语翻译在静电作用模式下,克林沙星与DNA骨架上的磷酸基团发生作用,其对ssDNA和dsDNA的猝灭程度应相等,而在插入作用模式下,ssDNA没有dsDNA的双螺旋结构,克林沙星应不对其发生猝灭作用.当发
英语翻译
在静电作用模式下,克林沙星与DNA骨架上的磷酸基
团发生作用,其对ssDNA和dsDNA的猝灭程度应相
等,而在插入作用模式下,ssDNA没有dsDNA的双螺
旋结构,克林沙星应不对其发生猝灭作用.当发生
沟槽作用模式时,由双链DNA变性得到的单链DNA
虽然大小沟槽被破坏了,但单链DNA是以线团状形
式存在于溶液中的,在线团的表面形成了可以与小
分子发生氢键作用的许多凹点,所以仍存在部分的
猝灭作用.

英语翻译在静电作用模式下,克林沙星与DNA骨架上的磷酸基团发生作用,其对ssDNA和dsDNA的猝灭程度应相等,而在插入作用模式下,ssDNA没有dsDNA的双螺旋结构,克林沙星应不对其发生猝灭作用.当发
Under the electrostatic model,clinafloxacin reacts with the phosphate group on the backbone of a DNA,and it exhibits similar fluorescence quenching effect on both ssDNA and dsDNA.But under the insertion effect model,and since ssDNA does not have the double-helical struacutre of dsDNA,clinafloxacin does not show any fluorescence quenching effect.When groove effect model takes place,even though the major and minor grooves of the sigle strand DNA derived from the doble-helical DNA are destroyed,the single strand DNA has an line-and-knots conformation,and surface of the knots have pockets that can form hydrogen bonds with small molecules.As a result,there is still some partial fluorescence quenching effect.

In the electrostatic mode, clinafloxacin the skeleton and DNA phosphate -
Mission occurred effects, and on the ssDNA dsDNA and the degree of quenching
And so on, and inserted in the role mod...

全部展开

In the electrostatic mode, clinafloxacin the skeleton and DNA phosphate -
Mission occurred effects, and on the ssDNA dsDNA and the degree of quenching
And so on, and inserted in the role model, the dual-ssDNA not dsDNA Lo
Rotary structure, and should not be clinafloxacin quenching their role. When a
Groove role model, the double-stranded DNA denaturation be single-stranded DNA
Although the size of the destruction of the trench, but a line single strand DNA--Mission
Presence in the solution of the online group can be formed on the surface and the small
Molecular hydrogen bonding in many Au point, so there is still part of the
Quenching effect.

收起