英语翻译Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase,nonenzymatic disproportionation,and reduction by deoxyhemoglobin,myoglobin,and tissue heme p

来源：学生作业帮助网 编辑：六六作业网 时间：2024/11/23 15:36:40
英语翻译NitriterepresentsacirculatingandtissuestorageformofNOwhosebioactivationismediatedbytheenzymatica

英语翻译Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase,nonenzymatic disproportionation,and reduction by deoxyhemoglobin,myoglobin,and tissue heme p
英语翻译
Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase,nonenzymatic disproportionation,and reduction by deoxyhemoglobin,myoglobin,and tissue heme proteins.Because the rate of NO generation from nitrite is linearly dependent on reductions in oxygen and pH levels,we hypothesized that nitrite would be reduced to NO in ischemic tissue and exert NO-dependent protective effects.Solutions of sodium nitrite were administered in the setting of hepatic and cardiac ischemia-reperfusion (I/R) injury in mice.In hepatic I/R,nitrite exerted profound dose-dependent protective effects on cellular necrosis and apoptosis,with highly significant protective effects observed at near-physiological nitrite concentrations.In myocardial I/R injury,nitrite reduced cardiac infarct size by 67%.Consistent with hypoxia-dependent nitrite bioactivation,nitrite was reduced to NO,S-nitrosothiols,N-nitros-amines,and iron-nitrosylated heme proteins within 1-30 minutes of reperfusion.Nitrite-mediated protection of both the liver and the heart was dependent on NO generation and independent of eNOS and heme oxygenase-1 enzyme activities.These results suggest that nitrite is a biological storage reserve of NO subserving a critical function in tissue protection from ischemic injury.These studies reveal an unexpected and novel therapy for diseases such as myocardial infarction,organ preservation and transplantation,and shock states.

英语翻译Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase,nonenzymatic disproportionation,and reduction by deoxyhemoglobin,myoglobin,and tissue heme p
亚硝酸盐是一个循环和组织中一氧化氮的存储形式,其生物活化作用是由黄嘌呤氧化还原酶,非酶歧化和还原血红蛋白,肌红蛋白减少,并组织血红素蛋白质酶介导的行动.因为一氧化氮的生成率呈线性亚硝酸盐在氧气和pH值减少依赖性,我们推测亚硝酸盐将减少到缺血组织中一氧化氮和一氧化氮的产生依赖的保护作用.亚硝酸钠管理解决方案是在肝脏和心脏缺血再灌注（I / R）在小鼠损伤的设置.在肝I / R,亚硝酸盐产生深刻的剂量依赖性保护作用的细胞坏死和细胞凋亡的保护作用十分显着,观察在接近生理浓度的亚硝酸盐.在心肌I / R损伤,亚硝酸盐降低67％心肌梗死面积.缺氧依赖亚硝酸盐生物活化作用一致,亚硝酸盐减至不,第S -亚硝基的N-亚硝胺,并在1-30分钟,再灌注铁亚硝基血红素蛋白质.亚硝酸盐介导双方的肝脏和心脏的保护依赖于NO的生成及eNOS独立和血红素氧合酶1的活动.这些结果表明,亚硝酸盐是一种不促进从在组织缺血损伤保护重要功能的生物存储储备.这些研究揭示出一种如心肌梗死,器官保存和移植,疾病,意外和震惊国家和新颖的疗法.

亚硝酸盐代表循环和组织储存由不bioactivation介导的酶作用的黄嘌呤氧化还原酶,依赖于类似哺乳,离子还原,deoxyhemoglobin,组织肌血红素的蛋白质。因为利率产生的线性相关亚硝酸盐在减少氧气和pH水平,我们假设亚硝酸盐没有被减少缺血组织和发挥一氧化氮保护作用。解决方案的管理对亚硝酸钠的肝的设置和心脏缺血-再灌注(I / R)受伤的老鼠。在肝脏缺血/再灌注组、亚硝酸盐深远的保护作用...

全部展开

亚硝酸盐代表循环和组织储存由不bioactivation介导的酶作用的黄嘌呤氧化还原酶,依赖于类似哺乳,离子还原,deoxyhemoglobin,组织肌血红素的蛋白质。因为利率产生的线性相关亚硝酸盐在减少氧气和pH水平,我们假设亚硝酸盐没有被减少缺血组织和发挥一氧化氮保护作用。解决方案的管理对亚硝酸钠的肝的设置和心脏缺血-再灌注(I / R)受伤的老鼠。在肝脏缺血/再灌注组、亚硝酸盐深远的保护作用存在剂量依赖于细胞坏死和凋亡保护作用,非常重要的观察到near-physiological亚硝酸盐含量。心肌缺血/再灌注损伤、亚硝酸盐心脏梗塞面积减少由67%。
符合hypoxia-dependent亚硝酸盐bioactivation、亚硝酸盐减少到不,S-nitrosothiols,N-nitros-amines,iron-nitrosylated血红素蛋白1-30分钟内再灌注。双方的保护肝脏和心脏的依赖于没有生成、独立和血红素oxygenase-1以挪士是塞特的酶活性。这些结果表明,是一种生物性亚硝酸盐的存储保留在组织一项至关重要的工作subserving缺血性损伤的保护。这些研究的结果说明想到的是,他的小说治疗疾病,如心肌梗死、器官保存和移植和休克状态。

收起

亚硝酸盐代表循环和组织储存由不同介导的酶作用的黄嘌呤氧化还原酶,依赖于类似哺乳,离子还原,,组织肌血红素的蛋白质。因为利率产生的线性相关亚硝酸盐在减少氧气和pH水平,我们假设没有被减少的亚硝酸盐缺血组织和发挥一氧化氮保护作用。解决方案的管理对亚硝酸钠的肝的设置和心脏缺血-再灌注(I / R)受伤的老鼠。在肝脏缺血/再灌注组、亚硝酸盐深远的保护作用存在剂量依赖于细胞坏死和凋亡保护作用,非常重要的观察...

全部展开

亚硝酸盐代表循环和组织储存由不同介导的酶作用的黄嘌呤氧化还原酶,依赖于类似哺乳,离子还原,,组织肌血红素的蛋白质。因为利率产生的线性相关亚硝酸盐在减少氧气和pH水平,我们假设没有被减少的亚硝酸盐缺血组织和发挥一氧化氮保护作用。解决方案的管理对亚硝酸钠的肝的设置和心脏缺血-再灌注(I / R)受伤的老鼠。在肝脏缺血/再灌注组、亚硝酸盐深远的保护作用存在剂量依赖于细胞坏死和凋亡保护作用,非常重要的观察到亚硝酸盐含量。心肌缺血/再灌注损伤、亚硝酸盐心脏梗塞面积减少由67%。符合亚硝酸盐、亚硝酸盐减少血红素蛋白1-30分钟内再灌注。双方的保护肝脏和心脏的依赖于没有生成、独立和血红素以挪士是塞特的酶活性。这些结果表明,是一种生物性亚硝酸盐的存储保留在组织一项至关重要的工作缺血性损伤的保护。这些研究的结果说明想到的是,他的小说治疗疾病,如心肌梗死、器官保存和移植和休克状态

收起

亚硝酸盐代表循环和组织储存由不bioactivation介导的酶作用的黄嘌呤氧化还原酶,依赖于类似哺乳,离子还原,deoxyhemoglobin,组织肌血红素的蛋白质。因为利率产生的线性相关亚硝酸盐在减少氧气和pH水平,我们假设没有被减少的亚硝酸盐缺血组织和发挥一氧化氮保护作用。解决方案的管理对亚硝酸钠的肝的设置和心脏缺血-再灌注(I / R)受伤的老鼠。在肝脏缺血/再灌注组、亚硝酸盐深远的保护作...

全部展开

亚硝酸盐代表循环和组织储存由不bioactivation介导的酶作用的黄嘌呤氧化还原酶,依赖于类似哺乳,离子还原,deoxyhemoglobin,组织肌血红素的蛋白质。因为利率产生的线性相关亚硝酸盐在减少氧气和pH水平,我们假设没有被减少的亚硝酸盐缺血组织和发挥一氧化氮保护作用。解决方案的管理对亚硝酸钠的肝的设置和心脏缺血-再灌注(I / R)受伤的老鼠。在肝脏缺血/再灌注组、亚硝酸盐深远的保护作用存在剂量依赖于细胞坏死和凋亡保护作用,非常重要的观察到near-physiological亚硝酸盐含量。心肌缺血/再灌注损伤、亚硝酸盐心脏梗塞面积减少由67%。符合hypoxia-dependent亚硝酸盐bioactivation、亚硝酸盐减少到不,S-nitrosothiols,N-nitros-amines,iron-nitrosylated血红素蛋白1-30分钟内再灌注。双方的Nitrite-mediated保护肝脏和心脏的依赖于没有生成、独立和血红素oxygenase-1以挪士是塞特的酶活性。这些结果表明,是一种生物性亚硝酸盐的存储保留在组织一项至关重要的工作subserving缺血性损伤的保护。这些研究的结果说明想到的是,他的小说治疗疾病,如心肌梗死、器官保存和移植和休克状态。

收起

以后大家有生物医药学领域的翻译问题，可以登陆鑫达医学翻译网站进行沟通。
提供【免费】、【专业】、【快捷】、【在线翻译】
对生物医药学翻译感兴趣的同学，可以与客服进行交流。
百度或Google搜索【鑫达医学翻译】 第一个网站即是。...

全部展开

以后大家有生物医药学领域的翻译问题，可以登陆鑫达医学翻译网站进行沟通。
提供【免费】、【专业】、【快捷】、【在线翻译】
对生物医药学翻译感兴趣的同学，可以与客服进行交流。
百度或Google搜索【鑫达医学翻译】 第一个网站即是。

收起

英语翻译Nitrite represents a circulating and tissue storage form of NO whose bioactivation is mediated by the enzymatic action of xanthine oxidoreductase,nonenzymatic disproportionation,and reduction by deoxyhemoglobin,myoglobin,and tissue heme p 英语翻译In order to ensure the quality of products andmake nitrosation reaction complete,excessive sulfuricacid and sodium nitrite are usually used to make thestarch-KI indicator blue in industrial production proc-esses.The excess quantity of sul 英语翻译Therefore,findings of tri-colored Tangs today are considered rare and valuable treasures,valued for their brilliant color and life-like shapes.Developed in the tradition of the green and brown glazed pottery of the Han Dynasty,it represen 英语翻译Tere is no doubt that the skylight is a pivotal moulding element for both exterior and interopr of the architecture.Light and space is the theme of the museum design.These were symbols that even the centures had been collected to represen 英语翻译We would like to extend our sincere thanks to you for attending xxx conference,we hope you had a wonderful and above all interesting time with us.Your private transfer to the golf course will depart tomorrow morning at 6:45am,our represen 烷基亚硝酸盐(alkyl nitrite)长期使用对人有什么有害处? 21．Some of the star signs are ________ by creatures． A．written B．stand for C．1iked D．represen翻译一下 求翻译 化学镀Pd catalysts supported on activated carbon felts (ACFs) with different metallic loadings were prepared by electrolessplating and evaluated for the reduction of nitrite in water in a batch reactor. Homogeneous Pd dispersionswere obt 请教一段英文合同的翻译,急用,谢谢!In the event that asum is expressed to be payable as liquidated damages, the Parties agree thatsuch sum is fair and reasonable in the circumstances where such liquidateddamages are payable, and represen 这句合同英语 英译汉 改进提高的地方?Now,Therefore,In Consideration Of The Recitals Specified Above That Shall Be Deemed To Be A Substantive Part Of This Agree¬ment,And The Mutual Covenants,Promises,Undertakings,Agreements,Represen 求一道英文化学题的翻译The action of concentrated H2SO4 on urea, (H2N)2CO, results in the production of a white crystalline solid X of formula H3NO3S. This is a monobasic acid. On treatment with sodium nitrite and dilute hydrochloric acid a 急:提问几道GRE数学题1.A/x + A/y=1.In this formula,x and yrepresent the time needed for each of two workers to complete the job alone; Arepresents the time it takes for both x and y to complete the job workingtogether.So each fraction represen 1.____ of this room ____ empty.A.Two-third; are B.Two-thirds; are C.Two-third; is D.Two-thirds; is2.The staff_______ about the arrangements.A.were quarreling B.was quarreling C.quarrel D.had quarreled3.Bill,along with three other men,____ to represen Uncle Chris,I’m glad to have heard from you again the other day.By the time got the email the day before yesterday,I had worried that if you had met some problems so that you couldn't respond my email.In fact ,I have been the physics class represen 英语翻译 英语翻译 英语翻译 英语翻译