英语翻译THE LETTER TO THE EDITORDear sir,随着测序技术的发展,更多的生物序列信息将会更好的帮助生物学者发现生物的奥秘.人类基因组测序已经完成,进入个人基因组时代是历史的必然.我们通过现

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英语翻译THELETTERTOTHEEDITORDearsir,随着测序技术的发展,更多的生物序列信息将会更好的帮助生物学者发现生物的奥秘.人类基因组测序已经完成,进入个人基因组时代是历史的必然.我们

英语翻译THE LETTER TO THE EDITORDear sir,随着测序技术的发展,更多的生物序列信息将会更好的帮助生物学者发现生物的奥秘.人类基因组测序已经完成,进入个人基因组时代是历史的必然.我们通过现
英语翻译
THE LETTER TO THE EDITOR
Dear sir,
随着测序技术的发展,更多的生物序列信息将会更好的帮助生物学者发现生物的奥秘.人类基因组测序已经完成,进入个人基因组时代是历史的必然.我们通过现代高通量测序技术完成了第一个亚洲人的基因测序,这将为序列参考提供更多的信息.我们与NCBI参考序列进行比对,发现我们的序列覆盖度达到了99.97%,然后以unique比对的reads组装出了这个人的92%的基因组.然后我们对基因的indels,snp和structural variation进行了分析,通过分析找到了接近两百万多个snp ,其中大约40多万个是新发现的;对于小片段的indels,我们发现了13万多的个,而这些indels大约59.1%都是novel的.而structural variation只发现了2682个,这可能与他的发生频率有关系.
之后,为了验证这些数据的可靠性,我么进行了基因分型和sanger验证,最后得出的结果是基因分型结果与测序结果有99.22%的一致性,而sanger结果是50个被检测的snp和indel有41(82%)的都能被GA测序测到.再一次证明了高通量的可靠性.通过我们的努力,以后序列比对的参考又多了一些信息.到目前为止,测过个人基因组的只有Watson 和Venter ,这次亚洲YH基因组的测序成功,又为基因组的比较提供了更全面的信息而不仅限于欧洲.通过比较着三个人的基因,我们发现每个人有各自独特的基因序列,又有相似的序列.不仅如此,我们还进行了单体型分析,还分析了基因型和已知疾病的关系.
我的研究意义在于,不仅测了第一个亚洲人的个人基因组,而且还验证了高通量方法的实用性与可靠性,高通量测序具有传统测序方法无法比拟的优势,它可以同时在一张芯片测上亿个DNA片段,而且非常准确,这为以后更快速的测定个人基因组打下了坚实基础.测定一个人的基因组是很多研究的前提,大规模测定个人基因组可以发现个人药物反应的机制,为个人特异性用药提供保障;测定一个人的基因组,可以对其基因缺陷进行分析,从而寻找治疗途径;在小孩未出生之前,个人基因组分析,可以应用于产前诊断,可以免去我们对已知遗传病的困扰;
如果做的好,我不计较分数,要多少给多少.

英语翻译THE LETTER TO THE EDITORDear sir,随着测序技术的发展,更多的生物序列信息将会更好的帮助生物学者发现生物的奥秘.人类基因组测序已经完成,进入个人基因组时代是历史的必然.我们通过现
这不是炎黄那文章么.
>最后一句话 :
在这里回答问题的没几个是分奴

英语翻译The letter is to( )from( ). Write the letters in order to make a new word.(BOAYEVQIGHLCDATFJKMNPRS) 题在下面:1.the 1st,3rd,and the 9th letter:( )2.the 13th,3rd and the 4th letter:( )3.the 6th,5th,22nd and 4th letter:( )Tongue TwisterElizabeth's birthday is on the third Th 英语翻译What letter is two letters to the left of the letter immediately to the right of the letter three letters to the left of the letter three letters to the right of the letter 英语翻译Which letter is two to the right of the letter immediately to the left of the letter three to the right of the letter immediately to the right of the letter The letter is to 英语翻译Notwithstanding the provisions of UCP600,it is a condition of this letter of credit that is we give notice of refusal of documents presented under this letter of credit,we shall retain the right to accept a waiver of discrepancies from th 英语翻译take the letter along 英语翻译1.This is to acknowledge the receipt of your letter dated August 7th requesting us to effect insurance on the appointed shipment for your account.We are pleased to inform you that we have coverde the above shipment with the People’s Ins 英语翻译A certain month of the year stars with the 4th letter of the alphabet .What is the FIRST letter of the month which is 4 months after this letter to the editor是什么意思 Who is the letter to? A letter addressed to the 英语翻译By confirmed,Irrevocable,Transferable and Divisible Letter of Credit to be available by sight draft,to reach the Sellers before the date of shipment and remain valid in CHINA until the 15th day (inclusive) from the date of shipment. 英语翻译求信用证条款翻译 the buyer shall open though a bank acceptable to the seller an irrevocable letter of credit at 45 days' sight to reach the seller not later than 25 april 2003.negotiation in China until 15th day after the date of 英语翻译Dear sir or madamThank you for your time to read my letter.With the coming of the 50th anniversary of our school,I’d like to be a volunteer.I’ll try my best to serve our distinguished guests with enthusiasm.I have a good understanding 英语翻译A recently published letter from Proust to the editior Vallette confirm the theory. 英语翻译Your letter arrived yesterday,and I was glad to hear from you.I’m now living with an American family in New York City,which is one of the biggest cities in the United States.Everyone of the family likes art and is very kind to me.Jim,th reply to the letter, reply the letter回信 哪个正确