机械英语翻译The above methods are all based on image analysis. There areseveral traditional, non-image based methods for quantification ofinternal granule structure. These methods include pycnometry [27],mercury porosimetry [19,28,29], nitrogen
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机械英语翻译The above methods are all based on image analysis. There areseveral traditional, non-image based methods for quantification ofinternal granule structure. These methods include pycnometry [27],mercury porosimetry [19,28,29], nitrogen
机械英语翻译
The above methods are all based on image analysis. There are
several traditional, non-image based methods for quantification of
internal granule structure. These methods include pycnometry [27],
mercury porosimetry [19,28,29], nitrogen adsorption technique or
BET analysis [28,30] and Inverse Gas Chromatography, IGC, [31].
Acquiring the internal granule structure by modern methods, such as
image-based techniques, is often costly due to operating and capital
costs of equipment such as X-ray micro-tomography (XMT), Magnetic
Resonance Imaging (MRI), and Transmission Electron Microscopy
(TEM). However, these are more accurate and give more information
which cannot otherwise be obtained by the traditional methods. XMT
has been used in the field of granulation technology for analysis of the
internal structure of granules [19] and tablets [32], external particle
shape [33] and characterisation of agglomerate structure for DEM
simulations [14].An important challenge of the granulation technology is to
produce consistent granule structure and shape which in turn lead
to more uniform properties such as strength and dissolution rate. This
is difficult without introducing a method to quantify the granule
structure. In this paper we use some structure descriptors such as
chord length distribution and phase function to enable quantification
of internal structure of granules.
The characterisation of granule strength [34–39] and structure [14]
has previously been reported. However, there is no work on the effect
of different operating conditions, such as impeller speed on the
internal granule structure. The objective of this work is to acquire the
internal structure of granules by high resolution X-ray microtomography
and to analyse it using a software package developed
by Stepanek et al. [40]. The granules used in this work were produced
at three different impeller speeds in a high shear granulator. The
measurement of strength of these granules by side crushing test
method has previously been reported [38,39,41]. An attempt has been
made to relate the acquired structure to granule strength.
不怎么通顺呀,要是满意的话,可以追加分的
机械英语翻译The above methods are all based on image analysis. There areseveral traditional, non-image based methods for quantification ofinternal granule structure. These methods include pycnometry [27],mercury porosimetry [19,28,29], nitrogen
The above methods are all based on image analysis.
上述方法都是基于图像分析.
There are several traditional,non-image based methods for quantification of internal granule structure.
有几种传统的,非基于图像的量化内部颗粒结构方法.
These methods include pycnometry [27],mercury porosimetry [19,28,29],nitrogen adsorption technique or
这些方法包括pycnometry、汞porosimetry[27](19、28、29]、氮气吸附技术或
BET analysis [28,30] and Inverse Gas Chromatography,IGC,[31].
BET分析[28,30]以及反气相色谱仪,或IGC[31].
Acquiring the internal granule structure by modern methods,such as image-based techniques,is often costly due to operating and capital costs of equipment such as X-ray micro-tomography (XMT),Magnetic Resonance Imaging (MRI),and Transmission Electron Microscopy(TEM).
用现代的方法获取内部颗粒结构,如影像学技术,往往是昂贵的,由于操作及资金成本,如x射线micro-tomography(XMT)、磁共振成像(MRI)和透射电子显微镜等设备(TEM).
However,these are more accurate and give more information which cannot otherwise be obtained by the traditional methods.
然而,这些都是更准确的,给出的信息更多,这些信息也无法用传统方法获得的.
XMT has been used in the field of granulation technology for analysis of the internal structure of granules [19] and tablets [32],external particle shape [33] and characterisation of agglomerate structure for DEM
XMT已被用于颗粒技术领域,分析颗粒(19]和片剂[32]的内在结构外部颗粒形状,[33]和DEM的结块性结构特征
simulations [14].
模拟[14].
An important challenge of the granulation technology is to produce consistent granule structure and shape which in turn lead to more uniform properties such as strength and dissolution rate.
颗粒技术上的一个重要的挑战是生产出结构和形状一致的颗粒,从而得到更均匀的性质,如强度、溶解率.
This is difficult without introducing a method to quantify the granulestructure.
如果没有一个定量研究颗粒结构的方法,这将是非常困难的.
In this paper we use some structure descriptors such as chord length distribution and phase function to enable quantification of internal structure of granules.
在本文中,我们使用一些结构描述符,如弦长分布和相位函数,从而量化颗粒的内部结构.
The characterisation of granule strength [34–39] and structure [14] has previously been reported.
各种颗粒的强度[34-39]和结构的特征[14]过去曾有过报告.
However,there is no work on the effect of different operating conditions,such as impeller speed on the internal granule structure.
然而,没有关于不同的操作条件对工作的影响,如叶轮速度对内部颗粒结构的影响的报告.
The objective of this work is to acquire the internal structure of granules by high resolution X-ray microtomography and to analyse it using a software package developed by Stepanek et al.[40].
本文的目的是利用高分辨x射线microtomography获得颗粒的内部结构,并使用一个由Stepanek 等人开发的软件来分析它.【40].
The granules used in this work were produced at three different impeller speeds in a high shear granulator.
这项工作使用的颗粒是在三种不同速度的叶轮高剪切造粒下产生的.
上述方法都是基于图像分析。有
一些传统方法,非基于量化
内部颗粒结构。这些方法包括pycnometry[27],
水星porosimetry(19、28、29]、氮气吸附技术或
28日,打赌分析[30]和反气相色谱仪,被选送[31]。
获取内部颗粒结构用现代的方法,例如
影像学技术,往往是昂贵的,由于操作和资本
成本等设备的x射线micro-...
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上述方法都是基于图像分析。有
一些传统方法,非基于量化
内部颗粒结构。这些方法包括pycnometry[27],
水星porosimetry(19、28、29]、氮气吸附技术或
28日,打赌分析[30]和反气相色谱仪,被选送[31]。
获取内部颗粒结构用现代的方法,例如
影像学技术,往往是昂贵的,由于操作和资本
成本等设备的x射线micro-tomography(XMT)、磁性
核磁共振成像(MRI)和透射电子显微镜
(TEM)。然而,这些都是更精确和给更多的信息
否则,不能用传统方法获得。XMT
已被用于造粒技术领域的分析
内部结构的颗粒(19]和药片[32],外部的粒子
[33]和形状结构的特征性的凝聚DEM
模拟[14]。一个重要的挑战是造粒技术
制造稳定的颗粒结构和形状从而领先
到更均匀的性质,如强度、溶出率。这
一种方法是困难而不致于颗粒,定量研究了吗
结构。在本文中,我们使用一些结构描述符等
弦长分布和相位函数,使量化
的内部结构的颗粒。
各种颗粒状的34-39特征性的力量[[14]]和结构
曾被报告过。但是,没有工作的效果
不同的操作条件,如叶轮速度
内部颗粒结构。本文的目的是获得的工作
内部结构的高分辨x射线microtomography颗粒
它使用,分析软件包开发的
通过Stepanek孙俐。【40]。 这项工作对颗粒用于也被制造出来了
在三个不同的叶轮速度在高剪切造粒。这
这些颗粒的强度的测量并排破碎试验
函数的方法有
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